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Interleukin-2
Description
Interleukins are a group of cytokines that are expressed by white blood cells. They intervene in the organismīs immune reactions, acting as a mediator in inflammation processes or as a colony stimulating factor of certain blood cells. Interleukin (IL-2) is a naturally occurring hormone secreted by T-cells. It stimulates the growth and differentiation of the T-cell response. When used in immunotherapy to treat cancer, IL-2 enhances the ability of the immune system to kill tumor cells and may interfere with the blood flow to the tumor.
This protein is a recombinant mutein (modified form) of human interleukin-2 (IL-2) expressed by a transformed Escherichia coli (E.Coli) bacterial cell line. Interleukin-2 is a non-glycosylated protein with a sequence - with two exceptions - homologous to human IL-2.
Also, unlike human IL-2, since it is expressed by bacteria, Interleukin-2 is not glycosylated.
It is a hydrophobic protein with a molecular weight of approximately 15,600 daltons (15.6 kDa).

Indications
· Renal Carcinoma
· Malignant Melanoma